Circulating microRNAs (miRNAs): Biomarkers for Lung Cancer
نویسندگان
چکیده
منابع مشابه
Micrornas as Stable Circulating Biomarkers for Lung Cancer Diagnosis
Background: Lung cancer is the leading cause of cancer mortality in the world, but there are no satisfactory biomarkers for lung cancer detection. MicroRNAs are small non-coding RNAs that regulate the gene expressions at the posttranscription level. Many microRNAs are dysregulated and shows specific expression patterns in human cancer. The aim of this study is to profile circulating microRNAs i...
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Early diagnosis of lung cancer by low-dose computed tomography is an effective strategy to reduce cancer mortality in high-risk individuals. However, recruitment of at-risk individuals with asymptomatic lung cancer still remains challenging. We developed a minimal invasive serum test, based on the detection of circulating microRNAs, which can identify at-risk individuals with asymptomatic early...
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Cancer is the leading cause of death in the world. Development of minimally invasive biomarkers for early detection of cancer is urgently needed to reduce high morbidity and mortality associated with malignancy. MicroRNAs (miRNAs) are small regulatory RNAs that modulate the activity of specific mRNA targets and play important roles in a wide range of physiologic and pathologic processes. Recent...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2015
ISSN: 0923-7534
DOI: 10.1093/annonc/mdv348.42